Autologous Serum
Eye DropsAn effective solution for dry eye disease

What are Autologous Serum Eye Drops?

Autologous serum eye drops (ASED) are many things: effective, well tolerated and full of substances that artificial tears cannot replicate in the treatment of dry eye disease. They may be an option if you have severe dry eye symptoms that do not respond to any other treatment such as artificial tears, punctal plugs, or Meibomian gland treatments such as Lipiflow.

Serum contains bioactive agents that may promote healthy cell growth and healing of the ocular surface, including albumin, vitamin A, and nerve and epidermal growth factors. Studies have demonstrated instances of ASED surpassing artificial drops in promoting comfort and improving the quality of the tear film.

How are Autologous Serum Eye Drops made?

Autologous means that the donor and the recipient are the same person. The eye drops in this case are made from your own blood. Red blood cells and clotting factors are removed, leaving behind blood serum. This is diluted with a sterile, preservative-free solution to produce a tear substitute that is unique to the patient, and contains many important growth factors and nutrients normally found in healthy tears.

Since blood and tears have an almost identical salinity and pH, there is no issue of burning or stinging upon instillation. The patient receives a 3-month supply of drops and is instructed to store all of the bottles in the freezer except for the current bottle they are using, which should be stored in the refrigerator, because they are non-preserved.